Hand holding vial for prp treatments close up

Platelet-Rich Plasma (PRP) 101: What is PRP & How Does PRP Work?

Platelet-Rich Plasma (PRP) therapy has quickly become one of the most talked-about regenerative treatments in modern aesthetic medicine. Instead of relying on synthetic ingredients or implants, PRP uses the body's own natural healing mechanisms to rejuvenate the skin, stimulate collagen production, and support hair growth.

Originally developed for sports medicine and injury recovery, PRP is now widely used in cosmetic dermatology and aesthetic medicine to improve skin texture, reduce signs of aging, and enhance overall skin health.

If you're considering PRP treatment, understanding how it works and what it can treat can help you decide whether it's the right option for your goals.

This guide explains everything you need to know about PRP, including how the treatment works, what results to expect, and how it compares to other aesthetic procedures.

What Is Platelet-Rich Plasma (PRP)?

Platelet-Rich Plasma (PRP) is a regenerative treatment that uses a concentrated portion of a patient's own blood to stimulate healing and tissue repair. The plasma contains platelets rich in growth factors that help encourage collagen production, cell regeneration, and improved circulation. When PRP is injected or applied to targeted areas of the skin or scalp, it can support skin rejuvenation, improve texture, and promote healthier hair growth.

High-angle woman getting neck prp treatment

How Does PRP Work?

PRP works by using the part of your blood that helps the body heal and repair tissue. Your blood is made up of several components, including red blood cells, white blood cells, plasma, and platelets. Platelets play an important role in healing because they contain proteins called growth factors that signal the body to repair damaged tissue and create new cells.

During a PRP treatment, a small sample of your blood is placed in a machine called a centrifuge. The centrifuge spins the blood quickly to separate its different parts. This process allows us to isolate the plasma that contains a high concentration of platelets.

The platelet-rich plasma is then injected into the treatment area. Once there, the platelets release growth factors that help stimulate collagen production, improve circulation, and support the body's natural repair process.

Over time, this can help improve skin texture, strengthen tissue, and support healthier hair follicles in the scalp. Because PRP works with the body's natural healing process, results usually appear gradually as the skin or scalp regenerates.

The PRP Treatment Process: Step-by-Step

PRP treatments are relatively straightforward and typically take about 45 to 60 minutes. While the details may vary depending on the treatment area, most procedures follow a similar process.

  1. Consultation and Treatment Planning

Before treatment, a consultation is typically scheduled to assess your skin or scalp concerns. During this appointment, we will review your medical history, discuss your goals, and determine whether PRP treatment in Edmonton is an appropriate option for your concerns.

This step helps ensure the treatment is tailored to your individual needs. Some patients use PRP primarily for skin rejuvenation, while others pursue it for hair restoration or scar improvement.

  1.  Draw

Once the treatment plan is confirmed, a small amount of blood is drawn from your arm. The amount is similar to what would be collected during a routine blood test. This blood sample will be used to create the platelet-rich plasma that will later be injected or applied to the treatment area.

  1. Centrifuge Processing

The blood sample is then placed into a centrifuge, a specialized machine that spins rapidly to separate the components of the blood. During this process, the plasma portion containing the concentrated platelets is isolated. This platelet-rich plasma contains growth factors that help stimulate tissue repair and collagen production. Once separated, the PRP is prepared for use in the treatment.

  1. Preparing the Treatment Area

Before the PRP is applied or injected, the treatment area is cleansed and disinfected. Depending on the treatment being performed, a topical numbing cream may be applied to help reduce discomfort. This step ensures the procedure is both safe and comfortable.

  1. PRP Injection or Application

Once the PRP is ready, it is introduced into the target area. How it is delivered depends on the treatment:

  • Skin Rejuvenation: PRP is injected directly into the skin.
  • Hair Restoration: PRP is injected into the scalp.
  • Collagen Stimulation: PRP is combined with microneedling.
  • Delicate Areas: For sensitive areas like under the eyes, PRP is administered through careful, targeted injections.
  1. Immediate Post-Treatment Response

After the procedure, the treated area may appear red or slightly swollen. Some patients also experience mild tenderness or small pinpoint marks from injections. These effects are typically temporary and are part of the body's normal response to treatment.

Close up woman getting prp injection

PRP Recovery and Results Timeline

PRP results develop gradually because the treatment stimulates the body's natural healing processes. Understanding the typical recovery timeline can help set realistic expectations.

Immediately After Treatment

Right after the procedure, you may notice redness, warmth, or mild swelling in the treated area. If microneedling is used, the skin may appear flushed, similar to a mild sunburn.

For scalp treatments, mild tenderness or tightness may occur at the injection sites. These reactions are temporary and usually improve within the first day or two.

First 24 Hours

During the first day, the skin may still look slightly red or sensitive. It is common to experience mild swelling or tightness during this period. Patients are typically advised to avoid touching or applying makeup to the treated area for the remainder of the day.

Days 2 to 3

By the second or third day, redness and swelling usually begin to subside. The skin may already start to feel smoother or refreshed. If microneedling was used, the skin may feel slightly dry or rough as the outer layer begins to renew itself.

Days 4 to 7

By the end of the first week, most visible signs of treatment have resolved. The skin may appear brighter and healthier as early healing continues. Some patients notice improved glow or texture at this stage, although the full benefits of PRP are still developing.

Weeks 2 to 4

During the second to fourth week, collagen production increases. The skin may begin to feel firmer and more even in tone. Subtle improvements in fine lines, texture, and overall skin quality may become noticeable during this stage.

Weeks 4 to 8

Between one and two months after treatment, PRP results often become more visible. Patients may notice smoother texture, improved elasticity, and healthier-looking skin. At this point, hair restoration patients may begin to see reduced shedding or early signs of hair thickening.

Two to Three Months

The most significant improvements typically appear around two to three months after treatment as collagen remodelling continues. Skin may appear firmer, smoother, and more radiant as the regenerative effects of PRP take place.

Man getting prp injection for alopecia

What Areas Can PRP Treat?

PRP is a versatile treatment that can address several aesthetic concerns, which is just one of the reasons why everyone's talking about this skin and hair fix. Because it stimulates collagen production and tissue repair, it is commonly used in a variety of areas.

Facial Skin Rejuvenation

PRP is frequently used to improve overall skin quality. Many patients choose PRP to help address early signs of aging and dull skin.

PRP improves overall skin quality while allowing other treatments to enhance specific areas of the face. For example, some patients combine regenerative therapies with subtle lip enhancement in order to balance volume and natural shape while still maintaining a soft, natural appearance.

PRP for Hair Restoration

PRP is also widely used to support hair growth in individuals experiencing early hair thinning. Many patients explore PRP as part of a broader hair loss treatment in Edmonton. When injected into the scalp, PRP delivers growth factors directly to the hair follicles. 

These signals may help stimulate follicle activity and improve circulation within the scalp. Over time, this can encourage healthier hair growth and may help slow the progression of hair thinning in some individuals.

Learn about hair transplant recovery and consider if a hair restoration treatment is right for you! 

Under-Eye Rejuvenation

The skin under the eyes is thin and delicate, which makes it more susceptible to signs of aging.PRP may be used to improve under-eye concerns such as dark circles, crepey skin, and mild hollowness. By stimulating collagen production in this area, PRP can help strengthen the skin and improve overall texture.

Acne Scar Improvement

PRP is often combined with microneedling to help improve the appearance of acne scars. Microneedling creates tiny channels in the skin that allow PRP to penetrate more effectively. 

The growth factors within the plasma can then stimulate collagen production and help repair damaged tissue. Over time, this may help soften the appearance of scars and improve overall skin smoothness.

PRP vs Botox vs Dermal Fillers

PRP works differently from many traditional aesthetic treatments. Rather than adding volume or relaxing muscles, PRP focuses on improving the overall health and quality of the skin by stimulating collagen production and cellular repair.

For example, Botox injections are commonly used to relax facial muscles that cause dynamic wrinkles such as forehead lines, frown lines, and crow's feet. By temporarily reducing muscle movement, Botox can soften expression lines and help prevent them from becoming deeper over time.

Dermal fillers work in another way entirely. We offer dermal filler injections in Edmonton that are designed to restore lost facial volume and enhance contours in areas such as the lips, cheeks, and smile lines. Hyaluronic acid-based fillers add structure beneath the skin, helping to smooth folds and create more balanced facial proportions.

PRP complements both of these approaches by focusing on skin regeneration. Instead of altering muscle movement or adding volume, it encourages the body to produce more collagen and improve tissue quality. Because of this, some patients choose to combine fillers with other treatments such as PRP or neuromodulators as part of a more comprehensive facial rejuvenation plan.

Frequently Asked Questions About PRP

Is PRP safe?

PRP is generally considered safe because it uses your own blood. When performed by trained professionals, the risk of complications is low.

How many PRP treatments are needed?

Many patients benefit from a series of treatments spaced about four to six weeks apart. The exact number of sessions depends on the treatment area and goals.

Does PRP hurt?

Most patients find PRP treatments manageable. A topical numbing cream is typically used to minimize discomfort.

Who Is a Good Candidate for PRP?

PRP is suitable for many individuals who want a natural approach to skin rejuvenation. You may be a good candidate if you:

  • Want to improve skin quality naturally
  • Have early signs of aging
  • Want to address mild acne scars
  • Are experiencing early hair thinning
  • Prefer treatments using your body's own biological material

Book a consultation to determine whether PRP is appropriate for your individual concerns.

How long do PRP results last?

Results can last anywhere from six months to a year, depending on the treatment area and individual factors.

Can PRP be combined with other treatments?

Yes, PRP is frequently combined with procedures such as microneedling, dermal fillers, or Botox injections to enhance overall results.

PRP Treatments at Serene Radiance

PRP therapy offers a natural approach to skin rejuvenation and hair restoration by working with the body's own regenerative abilities.

At our cosmetic and aesthetic clinic in Edmonton, treatments are performed in a professional medical aesthetic setting focused on personalized care and natural-looking results. Patients receive individualized treatment plans designed to support long-term skin health and confidence.

If you're interested in exploring regenerative treatments, scheduling a consultation can help determine whether PRP is the right option for your goals.